MP79-05 VALIDATION OF THE NOVEL 5-GROUP GLEASON GRADING SYSTEM: 3+5 DISEASE RISK MAY BE OVERESTIMATED

Patterns, art, and context: Donald Floyd Gleason and the development of the Gleason grading system.

The Gleason grading system is a standard method of assessing prostate cancer. Very little is known, however, about the person behind the system, Donald Floyd Gleason, MD, PhD. Our objective was to construct a biography of Gleason and show how his work advanced prostate cancer diagnosis. We reviewed Gleason's notes, letters, and publications with the Veteran's Administration Cooperative Urology ...

Contemporary Gleason grading and novel Grade Groups in clinical practice.

PURPOSE OF REVIEW The Gleason grading system provides important information for guiding prostate cancer patients' management and prognostication. The grading system underwent significant modifications over the past decade. In 2005 and more recently in 2014, the International Society of Urological Pathology (ISUP) held two consensus conferences to update prostate cancer grading. Recently, five p...

Prostate Cancer Grading: A Decade After the 2005 Modified Gleason Grading System.

Since 1966, when Donald Gleason, MD, first proposed grading prostate cancer based on its histologic architecture, there have been numerous changes in clinical and pathologic practices relating to prostate cancer. Patterns 1 and 2, comprising more than 30% of cases in the original publications by Gleason, are no longer reported on biopsy and are rarely diagnosed on radical prostatectomy. Many of...

Prostate Cancer Grading: A Decade After the 2005 Modified Gleason Grading System. - PubMed - NCBI

Abstract Since 1966, when Donald Gleason, MD, first proposed grading prostate cancer based on its histologic architecture, there have been numerous changes in clinical and pathologic practices relating to prostate cancer. Patterns 1 and 2, comprising more than 30% of cases in the original publications by Gleason, are no longer reported on biopsy and are rarely diagnosed on radical prostatectomy...

Gleason grading of prostate cancer. Contemporary approach.